Here is the documentation for using the web:

Click on anything blue and underlined.

When you change the color of the links or change the underline, you invalidate the entire user manual. When you do Flash and fancy 2.0 stuff, you invalidate the entire user manual. Even “click on images, too” is a big risk.

Sometimes it is worth confusing the user, but it always consider doing it the simple way.

Jakob Nielson agrees as the first part of his cautionary article about Web 2.0. Follow that (very dark blue) link, by the way. It is an excellent article.

If you are inclined to blow off Jakob, remember that it’s the law. A “click on the blue stuff” site is about 99% ADA-compliant already.